In the middle is a woman that under oath claimed she had sex with Prince Andrew when she was 17, at the time the picture was taken. On the left is Prince Andrew who claims he doesn't remember ever meeting her, the picture is fake for a whole bunch of reasons that are all sucked out of his or his lawyers thumb. The arm around her waist is not his, he wasn't wearing a suit and he always wears suits at parties because he is a royal, Epstein never took photos etc etc etc
On the right is the girlfriend or wife of Epstein who introduced them to each other.
For a longer story check the link I supplied. Or this
transcript of the interview